RNAi Experiment: TH:320A12 |
Ace View of TH:320A12
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Genes Inhibited |
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Gene Inhibited |
K04H4.1 (emb-9) |
Description of "K04H4.1" |
emb-9 encodes the alpha-1 chain of Type IV basement membrane collagen most closely equivalent to human COL4A1 (OMIM:120130) on the basis of biological function; EMB-9 forms heterotrimeric Type IV collagen with LET-2, the alpha-2-like chain, and is required for the assembly and/or secretion of LET-2; EMB-9 is essential for embryonic morphogenesis, particularly epidermal elongation, and for larval development; EMB-9 is expresed primarily by body wall muscles and some somatic cells of the gonad and is detected in nearly all basement membranes. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:9339671..9340866)
Transcript overlap: 1053 nt |
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Sliding Window |
Raw score: 1016
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "K04H4.1" Links |
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TH:320A12 Phenotypes |
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Larval |
Gro
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TH:320A12 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:320A12 (PCR_reagent) |
Remark |
Phenotype comment -- Not yet confirmed by independent RNA |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Date |
2000-11-16 |
Gene Plot of K04H4.1 |
Browse using GBrowse
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