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RNAi Experiment: TH:320D5 Ace View of TH:320D5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  D2045.6 (cul-1)
Description of "D2045.6"  cul-1 encodes a cullin, orthologous to Cdc53/Cul1 in S. cerevisiae and CUL-1 in humans (OMIM:603134), that is required both maternally and zygotically for developmentally programmed transitions from the G1 phase of the cell cycle to the GO phase or the apoptotic pathway, and that is probably also required for normally slow G1-to-S phase progression; CUL-1 physically interacts with eight Skp1-related proteins (SKR-1, -2, -3, -4, -7, -8, -9, and -10).
KOG Annotation  Cullins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:10470972..10472001)
Transcript overlap: 829 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 788
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "D2045.6" Links  Wormbase NCBI
TH:320D5 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
TH:320D5 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:320D5 (PCR_reagent)
Remark  Phenotype comment -- Not yet confirmed by independent RNA
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of D2045.6 Browse using GBrowse
Gene Graph