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RNAi Experiment: TH:320H4 Ace View of TH:320H4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C48D5.1 (nhr-6)
Description of "C48D5.1"  nhr-6 encodes a nuclear receptor of the NR4A4 subfamily that is orthologous to the mammalian NGFI-B receptors and the Drosophila HR38 nuclear receptor (DHR38) that has been implicated in molting and metamorphosis; by homology, NHR-6 likely functions as a transcription factor that, based upon RNAi experiments, is required for normal ovulation and/or spermathecal development or function; an nhr-6 reporter fusion is expressed primarily in the anterior and posterior spermatheca during L3 and L4 larval stages, with some weak and variable expression also observed in two chemosensory neurons; nhr-6 mRNA is expressed in an oscillating manner throughout larval development, in a pattern that is slightly irregular with respect to the timing of larval molts and that exhibits consistently lower expression at the times when these molts actually occur.
KOG Annotation  Nuclear receptors of the nerve growth factor-induced protein B type
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:3576872..3578062)
Transcript overlap: 912 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 828
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C48D5.1" Links  Wormbase NCBI
TH:320H4 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:320H4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:320H4 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of C48D5.1 Browse using GBrowse
Gene Graph