Link to T07C4.7.1Link to T07C4.7.2Link to T07C4.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T07C4.8Link to T07C4.7.1geneMap Link to T07C4.7.1Link to T07C4.7.2Link to T07C4.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to T07C4.8Link to T07C4.7.1geneMap
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RNAi Experiment: TH:321E4 Ace View of TH:321E4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T07C4.8 (ced-9)
Description of "T07C4.8"  ced-9 is required for control of programmed cell death during development; it encodes the only C. elegans homolog of BCL-2.
KOG Annotation  Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel
What's a KOG?
Evidence for Inhibition 
ePCR Status: Best_ePCR (III:10335142..10336307)
Transcript overlap: 579 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 517
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.587
Wormbase (BLAST) RNAi primary
External "T07C4.8" Links  Wormbase NCBI
Gene Inhibited  T07C4.7 (mev-1)
Description of "T07C4.7"  mev-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT C, INTEGRAL MEMBRANE PROTEIN, 15KD (SDHC; OMIM:602413), which when mutated leads to familial nonchromaffin paragangliomas type 3.
KOG Annotation  Succinate dehydrogenase, cytochrome b subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Top50_percentile_ePCR (III:10335142..10336307)
Transcript overlap: 406 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 364
Relative score: 0.704 (Best raw score= for Gene )
Specificity index: 0.413
External "T07C4.7" Links  Wormbase NCBI
TH:321E4 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:321E4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:321E4 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of T07C4.8 Browse using GBrowse
Gene Graph
Gene Plot of T07C4.7 Browse using GBrowse
Gene Graph