RNAi Card Page

RNAi Experiment: TH:321G10

Ace View of TH:321G10

Genes Inhibited

Gene Inhibited

ZK1010.7 (col-97)

Description of "ZK1010.7"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

ePCR	Status: Unique_ePCR (III:12992108..12993200) Transcript overlap: 976 nt
Sliding Window	Raw score: 871 Relative score: 1 (This gene has the best score for this RNAi reagent) Specificity index: 0.327
Wormbase (BLAST)	RNAi primary

External "ZK1010.7" Links

Gene Inhibited

Y54E10BL.2 (col-48)

Description of "Y54E10BL.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 100
Relative score: 0.115 (Best raw score= for Gene )
Specificity index: 0.038

External "Y54E10BL.2" Links

Gene Inhibited

ZC513.8 (col-43)

Description of "ZC513.8"

col-43 encodes a collagen that is individually dispensable for viability and gross morphology in mass RNAi screens.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 94
Relative score: 0.108 (Best raw score= for Gene )
Specificity index: 0.035

External "ZC513.8" Links

Gene Inhibited

T21B4.2 (col-85)

Description of "T21B4.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 126
Relative score: 0.145 (Best raw score= for Gene )
Specificity index: 0.047

External "T21B4.2" Links

Gene Inhibited

F54B11.2 (col-44)

Description of "F54B11.2"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 379
Relative score: 0.435 (Best raw score= for Gene )
Specificity index: 0.142

External "F54B11.2" Links

Gene Inhibited

F11G11.12 (col-73)

Description of "F11G11.12"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 172
Relative score: 0.197 (Best raw score= for Gene )
Specificity index: 0.065

External "F11G11.12" Links

Gene Inhibited

C27H5.5 (col-36)

Description of "C27H5.5"

col-36 encodes a collagen protein; expressed during the L1 to L2 and L2 to dauer larval stage molts.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 132
Relative score: 0.152 (Best raw score= for Gene )
Specificity index: 0.05

External "C27H5.5" Links

Gene Inhibited

C09G5.5 (col-80)

Description of "C09G5.5"

Associated GO Term : structural constituent of cuticle

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 227
Relative score: 0.261 (Best raw score= for Gene )
Specificity index: 0.085

External "C09G5.5" Links

Gene Inhibited

F01G12.5 (let-2)

Description of "F01G12.5"

let-2 encodes an alpha-2 type IV collagen, probably most closely equivalent to the human gene COL4A2 (OMIM:120090) on the basis of biological function; LET-2 is required for embryonic development and is a component of the basement membrane between muscle and hypodermis; LET-2 interacts with UNC-105, a mechanosensory ion channel of the degenerin ion channel superfamily that is expressed in muscle and required for normal growth, muscle contraction, and muscle organization.

KOG Annotation

Collagens (type IV and type XIII), and related proteins

Evidence for Inhibition

Sliding Window

Raw score: 580
Relative score: 0.645 (Best raw score= for Gene )
Specificity index: 0.211

External "F01G12.5" Links

TH:321G10 Phenotypes

Phenotype

WTDIC phenotype -- Embryonic development normal

TH:321G10 Experiment Details

Ace View

Laboratory