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RNAi Experiment: TH:323E4 Ace View of TH:323E4
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T21C12.2 (hpd-1)
Description of "T21C12.2"  hpd-1 encodes a 4-hydroxyphenylpyruvate dioxygenase that is required for normally short lifespan and negative regulation of the dauer larval stage, with loss of hpd-1 function prolonging lifespan and promoting dauer formation; hpd-1 is a (perhaps evolutionarily conserved) target of transcriptional activation by DAF-16; HPD-1 is orthologous to human HPD (OMIM:276710, mutated in tyrosinemia type III).
KOG Annotation  4-hydroxyphenylpyruvate dioxygenase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:10535890..10537507)
Transcript overlap: 896 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 854
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "T21C12.2" Links  Wormbase NCBI
TH:323E4 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:323E4 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:323E4 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of T21C12.2 Browse using GBrowse
Gene Graph