Link to M142.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: TH:324A11 Ace View of TH:324A11
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  M142.1 (unc-119)
Description of "M142.1"  unc-119 encodes a novel protein that is highly conserved amongst metazoans; unc-119 activity is required for proper development of the nervous system, including axonal branching and fasciculation, and hence, for normal movement, chemosensation, and feeding; unc-119 is expressed pan-neuronally beginning in the early embryo (~60 cells) and continuing through adulthood; although the molecular function of UNC-119 is not yet known, human UNC119, which can rescue C. elegans unc-119 mutant animals, is reported to function as a receptor-associated activator of signal transduction; thus, UNC-119 may be part of a signal transduction pathway that mediates axonal patterning in response to external developmental cues.
KOG Annotation  Photoreceptor synaptic vesicle protein HRG4/UNC-119
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:10907429..10908753)
Transcript overlap: 706 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 643
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "M142.1" Links  Wormbase NCBI
TH:324A11 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:324A11 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:324A11 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of M142.1 Browse using GBrowse
Gene Graph