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RNAi Experiment: TH:324e8 Ace View of TH:324e8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F54C8.3 (emb-30)
Description of "F54C8.3"  emb-30 encodes an anaphase-promoting complex/cyclosome (APC/C) component orthologous to mammalian APC-4 and Schizosaccharomyces pombe Lid1; EMB-30 is required for the metaphase-to-anaphase transition during meiosis and mitosis, for establishing anterior-posterior polarity in the early embryo, and for proper localization of germline granules and the maternally provided PAR-2 and PAR-3 proteins.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9435687..9437302)
Transcript overlap: 1215 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1089
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F54C8.3" Links  Wormbase NCBI
TH:324e8 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
TH:324e8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:324e8 (PCR_reagent)
Remark  Phenotype comment -- Confirmed in independent study (Furuta et al., 2000).
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of F54C8.3 Browse using GBrowse
Gene Graph