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RNAi Experiment: TH:326A8 Ace View of TH:326A8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F56A8.7 (unc-64)
Description of "F56A8.7"  unc-64 encodes syntaxin, an plasma membrane receptor for intracellular vesicles that is orthologous to vertebrate syntaxin 1A (OMIM:186590) and Drosophila Syx1A; UNC-64 is required for normal locomotion and possibly also for insulin secretion; as an essential component of the core synaptic vesicle fusion machinery, UNC-64 interacts with UNC-13, a diacylglycerol-binding protein, and SNB-1/synaptobrevin; UNC-64 protein levels are reduced in an unc-18 mutant background; unc-64 mutations can be suppressed by mutations in slo-1, a calcium-activated potassium channel; UNC-64 is expressed ubiquitously in the nervous system and in secretory cells such as the uv1 cell in the vulva and excretory gland cells.
KOG Annotation  SNARE protein Syntaxin 1 and related proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:13277893..13280115)
Transcript overlap: 620 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 515
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F56A8.7" Links  Wormbase NCBI
TH:326A8 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:326A8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:326A8 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of F56A8.7 Browse using GBrowse
Gene Graph