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RNAi Experiment: TH:327B2 Ace View of TH:327B2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F23H11.8 (pef-1)
Description of "F23H11.8"  pef-1 encodes an ortholog of the rhodopsin-specific serine/threonine phosphatase RdgC in D. melanogaster and of RdgC-related proteins in humans (PPEF1 and PPEF2; OMIM:300109 and OMIM:602256); PEF-1 has a EF-hand calcium-binding domain, and is peripherally bound to the plasma membrane by myristoylation and palmitoylation; pef-1 has no known mutant phenotype, but is expressed in several anterior amphid neurons, from what appears to be the 3-fold embryo stage onward; on the basis of its expression and its orthology, PEF-1 may negatively regulate signalling through serpentine receptors such as STR-2.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:920619..922093)
Transcript overlap: 676 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 636
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F23H11.8" Links  Wormbase NCBI
TH:327B2 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:327B2 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:327B2 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of F23H11.8 Browse using GBrowse
Gene Graph