RNAi Experiment: TH:327B2 |
Ace View of TH:327B2
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Genes Inhibited |
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Gene Inhibited |
F23H11.8 (pef-1) |
Description of "F23H11.8" |
pef-1 encodes an ortholog of the rhodopsin-specific serine/threonine phosphatase RdgC in D. melanogaster and of RdgC-related proteins in humans (PPEF1 and PPEF2; OMIM:300109 and OMIM:602256); PEF-1 has a EF-hand calcium-binding domain, and is peripherally bound to the plasma membrane by myristoylation and palmitoylation; pef-1 has no known mutant phenotype, but is expressed in several anterior amphid neurons, from what appears to be the 3-fold embryo stage onward; on the basis of its expression and its orthology, PEF-1 may negatively regulate signalling through serpentine receptors such as STR-2. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:920619..922093)
Transcript overlap: 676 nt |
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Sliding Window |
Raw score: 636
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F23H11.8" Links |
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TH:327B2 Phenotypes |
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Phenotype |
WTDIC phenotype -- Embryonic development normal
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TH:327B2 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:327B2 (PCR_reagent) |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Delivery Method |
Injection |
Date |
2000-11-16 |
Gene Plot of F23H11.8 |
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