| RNAi Experiment: TH:327F7 |
Ace View of TH:327F7
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| Genes Inhibited |
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| Gene Inhibited |
C44B11.3 (mec-12) |
| Description of "C44B11.3" |
mec-12 encodes a novel C. elegans alpha-tubulin that is unique amongst C. elegans alpha tubulins in that it may be subject to post-translational acetylation; MEC-12 is required for normal mechanosensory response to gentle touch, and specifically for formation of the 15-protofilament microtubule bundle present in the touch receptor neurons; mec-12 interacts genetically with mec-5, which encodes a unique C. elegans collagen secreted by the hypodermis; MEC-12 is highly expressed in the touch neurons as well as in several other neurons that do not contains the microfilament bundle, such as the ventral cord motorneurons. |
| KOG Annotation |
Alpha tubulin
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| Evidence for Inhibition |
| ePCR |
Status: Unique_ePCR (III:3133617..3135026)
Transcript overlap: 741 nt |
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| Sliding Window |
Raw score: 699
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
| Wormbase (BLAST) |
RNAi primary |
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| External "C44B11.3" Links |
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| TH:327F7 Phenotypes |
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| Phenotype |
WTDIC phenotype -- Embryonic development normal
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| TH:327F7 Experiment Details |
Ace View |
| Laboratory |
TH |
| RNAi Reagent & Type |
TH:327F7 (PCR_reagent) |
| Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
| Delivery Method |
Injection |
| Date |
2000-11-16 |
| Gene Plot of C44B11.3 |
Browse using GBrowse
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