RNAi Experiment: TH:334H6 |
Ace View of TH:334H6
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Genes Inhibited |
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Gene Inhibited |
H04J21.2 (srd-69) |
Description of "H04J21.2" |
Associated GO Term : G-protein coupled receptor activity |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:2362822..2364963)
Transcript overlap: 711 nt |
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External "H04J21.2" Links |
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Gene Inhibited |
H04J21.3 (gip-1) |
Description of "H04J21.3" |
gip-1 encodes the C. elegans homolog of Saccharomyces cerevisiae Spc98p, a gamma-tubulin-binding protein that with Spc97p forms part of a gamma-tubulin ring complex that can nucleate microtubule formation in vitro and in vivo; in C. elegans, GIP-1 is essential for embryogenesis and required for formation of centrosomal asters during interphase and formation of the mitotic spindle, but not for formation of mitotic asters; GIP-1 colocalizes with TBG-1/gamma-tubulin to centrosomes during interphase and mitosis; GIP-1 and TBG-1 are required reciprocally for centrosomal localization. |
Evidence for Inhibition |
Sliding Window |
Raw score: 1491
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "H04J21.3" Links |
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TH:334H6 Phenotypes |
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Phenotype |
WTDIC phenotype -- Embryonic development normal
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TH:334H6 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:334H6 (PCR_reagent) |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Delivery Method |
Injection |
Date |
2000-11-16 |
Gene Plot of H04J21.3 |
Browse using GBrowse
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Gene Plot of H04J21.2 |
Browse using GBrowse
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