Ace View of TH:337B10 | |||
Gene Inhibited | Y39A1B.3 (dpy-28) | ||
Description of "Y39A1B.3" | dpy-28 encodes a non-SMC condensin subunit homolog, similar to XCAP-D2 in Xenopus, Cnd1 in S. pombe, and Ycs4p in S. cerevisiae, that is required for negative, chromosome-wide regulation of X-chromosomal genes in XX but not XO animals (dosage compensation), and for some undetermined aspect of body morphogenesis; DPY-28 is part of a multiprotein 'dosage compensation' complex with DPY-26, DPY-27 and MIX-1. | ||
KOG Annotation  | Chromosome condensation complex Condensin, subunit D2 |
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Evidence for Inhibition | |||
External "Y39A1B.3" Links | |||
Phenotype | WTDIC phenotype -- Embryonic development normal |
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Laboratory | TH | ||
RNAi Reagent & Type | TH:337B10 (PCR_reagent) | ||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||
Delivery Method | Injection | ||
Date | 2000-11-16 | ||
Gene Plot of Y39A1B.3 | |||