Ace View of TH:340D12 | ||||
Gene Inhibited | T20B12.8 (hmg-4) | |||
Description of "T20B12.8" | hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development. | |||
KOG Annotation  | Nucleosome-binding factor SPN, POB3 subunit |
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Evidence for Inhibition | ||||
External "T20B12.8" Links | ||||
Gene Inhibited | C32F10.5 (hmg-3) | |||
Description of "C32F10.5" | Associated GO Term : DNA binding | |||
KOG Annotation  | Nucleosome-binding factor SPN, POB3 subunit |
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Evidence for Inhibition |
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External "C32F10.5" Links | ||||
Embryonic | Emb Penetrance None reported | |||
Laboratory | TH | |||
RNAi Reagent & Type | TH:340D12 (PCR_reagent) | |||
Remark | Phenotype comment -- Phenotype confirmed by second independent RNA (RNA2). | |||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | |||
Date | 2000-11-16 | |||
Gene Plot of T20B12.8 | ||||
Gene Plot of C32F10.5 | ||||