Link to T20B12.7.1Link to T20B12.7.2Link to T20B12.8RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to C32F10.2Link to C32F10.5RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: TH:340D12 Ace View of TH:340D12
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T20B12.8 (hmg-4)
Description of "T20B12.8"  hmg-4 encodes a protein with strong similarity to the highly conserved high mobility group protein SSRP1 (structure-specific DNA recognition protein); by homology, HMG-4 is predicted to be a member of the FACT (facilitates chromatin transcription) complex that functions as a transcription elongation factor; RNAi experiments indicate that hmg-4 is required for locomotion and larval development, and required redundantly with hmg-3, its paralog, for embryonic development.
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:7379978..7380822)
Transcript overlap: 783 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 741
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.892
Wormbase (BLAST) RNAi primary
External "T20B12.8" Links  Wormbase NCBI
Gene Inhibited  C32F10.5 (hmg-3)
Description of "C32F10.5"  Associated GO Term : DNA binding
KOG Annotation  Nucleosome-binding factor SPN, POB3 subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 90
Relative score: 0.121 (Best raw score= for Gene )
Specificity index: 0.108
External "C32F10.5" Links  Wormbase NCBI
TH:340D12 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
TH:340D12 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:340D12 (PCR_reagent)
Remark  Phenotype comment -- Phenotype confirmed by second independent RNA (RNA2).
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of T20B12.8 Browse using GBrowse
Gene Graph
Gene Plot of C32F10.5 Browse using GBrowse
Gene Graph