Link to R10E11.1aLink to R10E11.1bRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentLink to F40F12.7.2Link to F40F12.7.1Link to K03H1.10.2Link to K03H1.10.1geneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: TH:341A3 Ace View of TH:341A3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  R10E11.1 (cbp-1)
Description of "R10E11.1"  cbp-1 encodes a homolog of the mammalian transcriptional cofactors CBP (OMIM:600140) and p300 (E1A-BINDING PROTEIN, 300-KD; OMIM:602700) that have been shown to possess histone acetyltransferase activity, and which, when mutated, lead to Rubinstein-Taybi syndrome (OMIM:180849) and colorectal cancer (OMIM:114500); at least one splicing form of CBP-1 exhibits histone acetyltransferase (HAT) activity in vitro and has a glutamine/asparagine-rich domain; CBP-1 is required during embryogenesis for differentiation of all non-neuronal somatic cell types; CBP-1 is expressed very early in embryogenesis, suggesting that it may interact with maternally provided transcription factors, such as SKN-1, to specific developmental fates.
KOG Annotation  CREB binding protein/P300 and related TAZ Zn-finger proteins
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:9766828..9768141)
Transcript overlap: 1020 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 978
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "R10E11.1" Links  Wormbase NCBI
TH:341A3 Phenotypes Help with Phenotypes
Phenotype  WTDIC phenotype -- Embryonic development normal
TH:341A3 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:341A3 (PCR_reagent)
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Delivery Method  Injection
Date  2000-11-16
Gene Plot of R10E11.1 Browse using GBrowse
Gene Graph