| Ace View of TH:341C7 | |||||||||
| Gene Inhibited | T07C4.8 (ced-9) | ||||||||
| Description of "T07C4.8" | ced-9 is required for control of programmed cell death during development; it encodes the only C. elegans homolog of BCL-2. | ||||||||
| KOG Annotation | Anti-apoptotic Bcl-2 family proteins, prevent opening of mitochondrial porin channel |
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| Evidence for Inhibition |
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| External "T07C4.8" Links |   |
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| Gene Inhibited | T07C4.7 (mev-1) | ||||||||
| Description of "T07C4.7" | mev-1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT C, INTEGRAL MEMBRANE PROTEIN, 15KD (SDHC; OMIM:602413), which when mutated leads to familial nonchromaffin paragangliomas type 3. | ||||||||
| KOG Annotation | Succinate dehydrogenase, cytochrome b subunit |
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| Evidence for Inhibition |
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| External "T07C4.7" Links | |
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| Gene Inhibited | Y67H2A.9 | ||||||||
| Evidence for Inhibition |
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| External "Y67H2A.9" Links | |
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| Phenotype | WTDIC phenotype -- Embryonic development normal |
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| Laboratory | TH | ||||||||
| RNAi Reagent & Type | TH:341C7 (PCR_reagent) | ||||||||
| Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2000-11-16 | ||||||||
| Gene Plot of T07C4.8 | |||||||||
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| Gene Plot of T07C4.7 | |||||||||
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| Gene Plot of Y67H2A.9 | |||||||||
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