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RNAi Experiment: TH:341C8 Ace View of TH:341C8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y47D3B.7 (sbp-1)
Description of "Y47D3B.7"  sbp-1 encodes a basic helix-loop-helix (bHLH) transcription factor homologous to the mammalian Sterol Regulatory Element Binding Proteins (SREBPs, OMIM:184756, overexpression of nuclear form of SREBP-1c is associated with insulin resistance and features of congenital generalized lipodystrophy); in C. elegans, SBP-1 activity is required for normal lipid metabolism and wild-type levels of lipogenic enzyme expression, as well as for embryonic and larval development; sbp-1 expression is detected exclusively in the intestine, the major site of fat storage, from early embryogenesis through adulthood.
KOG Annotation  Predicted DNA-binding protein
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:11436958..11437678)
Transcript overlap: 616 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 566
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "Y47D3B.7" Links  Wormbase NCBI
TH:341C8 Phenotypes Help with Phenotypes
Larval  Gro
Adult  Bmd
TH:341C8 Experiment Details Ace View
Laboratory  TH
RNAi Reagent & Type  TH:341C8 (PCR_reagent)
Remark  Phenotype comment -- Phenotype confirmed by second independent RNA (RNA2).
Reference  Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...."
Date  2000-11-16
Gene Plot of Y47D3B.7 Browse using GBrowse
Gene Graph