RNAi Experiment: TH:341D7 |
Ace View of TH:341D7
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Genes Inhibited |
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Gene Inhibited |
T20H4.5 |
Description of "T20H4.5" |
The T20H4.5 gene encodes an ortholog of the human gene NADH DEHYDROGENASE-UBIQUINONE FE-S PROTEIN 8 23 KDA SUBUNIT; MITOCHONDRIAL COMPLEX I TYKY SUBUNIT (NDUFS8; OMIM:602141), which when mutated leads to Leigh syndrome (OMIM:256000); the T20H4.5 protein is predicted to be mitochondrial with 52% accuracy. |
KOG Annotation  |
NADH:ubiquinone oxidoreductase, NDUFS8/23 kDa subunit
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:7233051..7233584)
Transcript overlap: 421 nt |
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Sliding Window |
Raw score: 381
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "T20H4.5" Links |
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TH:341D7 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
TH:341D7 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:341D7 (PCR_reagent) |
Remark |
Phenotype comment -- A second independent RNA (RNA2) yielded a weaker phenotype (early larval arrest). |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Date |
2000-11-16 |
Gene Plot of T20H4.5 |
Browse using GBrowse
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