RNAi Experiment: TH:341c1 |
Ace View of TH:341c1
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Genes Inhibited |
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Gene Inhibited |
F35G12.10 (asb-1) |
Description of "F35G12.10" |
asb-1 encodes a homolog of ATP synthase B, closely similar to its paralog ASB-2, that is required for embryonic viability and for the normal proliferation of germline cells; asb-1 is preferentially expressed in germline cells, while RNAi of asb-1 causes embryonic lethality and sterility with a defective progression to meiosis. |
KOG Annotation  |
Mitochondrial F1F0-ATP synthase, subunit b/ATP4
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:4595199..4595783)
Transcript overlap: 496 nt |
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Sliding Window |
Raw score: 433
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F35G12.10" Links |
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TH:341c1 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
TH:341c1 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:341c1 (PCR_reagent) |
Remark |
Phenotype comment -- Confirmed with independent dsRNA (F35G12.10-RNA2; similar DIC phenotype, but progeny test was not embryonic lethal). |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Date |
2000-11-16 |
Gene Plot of F35G12.10 |
Browse using GBrowse
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