RNAi Experiment: TH:341h5 |
Ace View of TH:341h5
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Genes Inhibited |
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Gene Inhibited |
F43C1.2 (mpk-1) |
Description of "F43C1.2" |
mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro. |
KOG Annotation  |
Mitogen-activated protein kinase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:4218064..4219492)
Transcript overlap: 828 nt |
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Sliding Window |
Raw score: 744
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F43C1.2" Links |
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TH:341h5 Phenotypes |
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Adult |
Ste
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TH:341h5 Experiment Details |
Ace View |
Laboratory |
TH |
RNAi Reagent & Type |
TH:341h5 (PCR_reagent) |
Remark |
Phenotype comment -- Very few or no embryos found. |
Reference |
Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." |
Date |
2000-11-16 |
Gene Plot of F43C1.2 |
Browse using GBrowse
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