Ace View of TH:343A6 | ||||||
Gene Inhibited | B0336.2 (arf-1.2) | |||||
Description of "B0336.2" | arf-1 encodes an ADP-ribosylation factor homolog required in vivo for embryonic development, fertility, locomotion, vulval development, and cuticular synthesis; ARF proteins are N-myristoylated GTPases that regulate membrane traffic and the actin cytoskeleton, and that activate both phospholipase D1 (PLD1) and phosphatidylinositol 4-phosphate 5-kinase. | |||||
KOG Annotation  | GTP-binding ADP-ribosylation factor Arf1 |
|||||
Evidence for Inhibition |
|
|||||
External "B0336.2" Links | ||||||
Embryonic | Emb Penetrance None reported | |||||
Laboratory | TH | |||||
RNAi Reagent & Type | TH:343A6 (PCR_reagent) | |||||
Remark | Phenotype comment -- Confirmed with independent dsRNA (B0336.2-RNA2; similar phenotype). | |||||
Reference | Gonczy P et al. (2000) Nature "Functional genomic analysis of cell division in C. elegans using RNAi of genes on ...." | |||||
Date | 2000-11-16 | |||||
Gene Plot of B0336.2 | ||||||