Ace View of WBRNAi00038579 | ||||||
Gene Inhibited | B0218.3 (pmk-1) | |||||
Description of "B0218.3" | pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway. | |||||
KOG Annotation  | Mitogen-activated protein kinase |
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Evidence for Inhibition |
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External "B0218.3" Links | ||||||
Phenotype | Esp |
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Laboratory | AU | |||||
RNAi Reagent & Type | probe_1:F42G8 (Unknown_reagent_type) | |||||
Strain | FK171 | |||||
Remark | Some enhancement of the Esp phenotype of the mek-1(ks54) mutant was seen in mek-1(ks54),pmk-1(RNAi) animals. | |||||
Reference | Kim DH et al. (2004) Proceedings of the National Academy of Sciences USA "Integration of Caenorhabditis elegans MAPK pathways mediating immunity and ...." | |||||
Delivery Method | Bacterial_feeding | |||||
Date | 2004-7-27 | |||||
Gene Plot of B0218.3 | ||||||