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RNAi Experiment: WBRNAi00038579 Ace View of WBRNAi00038579
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  B0218.3 (pmk-1)
Description of "B0218.3"  pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1050
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "B0218.3" Links  Wormbase NCBI
WBRNAi00038579 Phenotypes Help with Phenotypes
Phenotype  Esp
WBRNAi00038579 Experiment Details Ace View
Laboratory  AU
RNAi Reagent & Type  probe_1:F42G8 (Unknown_reagent_type)
Strain  FK171
Remark  Some enhancement of the Esp phenotype of the mek-1(ks54) mutant was seen in mek-1(ks54),pmk-1(RNAi) animals.
Reference  Kim DH et al. (2004) Proceedings of the National Academy of Sciences USA "Integration of Caenorhabditis elegans MAPK pathways mediating immunity and ...."
Delivery Method  Bacterial_feeding
Date  2004-7-27
Gene Plot of B0218.3 Browse using GBrowse
Gene Graph