Link to T28F12.2g.3Link to T28F12.2d.2Link to T28F12.2fLink to T28F12.2a.2Link to T28F12.2d.3Link to T28F12.2g.4Link to T28F12.2a.1Link to T28F12.2eLink to T28F12.2bLink to T28F12.2g.1Link to T28F12.2g.5Link to T28F12.2g.2Link to T28F12.2cLink to T28F12.2d.1RNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to Y75B8A.2bLink to Y75B8A.2aRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentgeneMap Link to Y47D3A.4Link to Y47D3A.5RNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi ReagentRNAi 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Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: WBRNAi00059886 Ace View of WBRNAi00059886
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  T28F12.2 (unc-62)
Description of "T28F12.2"  unc-62 encodes a Meis-class homeodomain protein required for posterior embryonic morphogenesis, male tail morphogenesis, commissure formation by VD and DD motor neurons, vulval morphogenesis, and normal locomotion; UNC-62 is orthologous to Drosophila HOMOTHORAX; both maternal-effect unc-62 alleles and the zygotic lethal unc-62(s472) allele phenotypically resemble mutations of the caudal ortholog pal-1; RNAi of the Pbc-class ceh-20 and ceh-40 homeodomain genes strongly enhances the hypomorphic unc-62(e644) allele to give either a strong loss-of-function or null-like phenotype, while overexpression of ceh-20 enhances the lethality of some unc-62 alleles.
Evidence for Inhibition 
Sliding Window Raw score: 1376
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.672
Wormbase (BLAST) RNAi primary
External "T28F12.2" Links  Wormbase NCBI
Gene Inhibited  Y75B8A.2 (nob-1)
Description of "Y75B8A.2"  The nob-1 gene encodes one of three C. elegans posterior group homeodomain transcription factors orthologous to Drosophila Abd-B and the vertebrate Hox9-13 proteins; NOB-1, along with an additional posterior Hox ortholog, PHP-3, is required during embryogenesis for proper fate specification and morphogenesis of cells in the posterior region.
KOG Annotation  Transcription factor Abd-B, contains HOX domain
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 192
Relative score: 0.323 (Best raw score= for Gene )
Specificity index: 0.217
External "Y75B8A.2" Links  Wormbase NCBI
Gene Inhibited  Y47D3A.5
Evidence for Inhibition 
Sliding Window Raw score: 98
Relative score: 0.165 (Best raw score= for Gene )
Specificity index: 0.111
External "Y47D3A.5" Links  Wormbase NCBI
WBRNAi00059886 Phenotypes Help with Phenotypes
Phenotype  Mig unc-62 RNAi shortens the anterior migration of QR descendents.
WBRNAi00059886 Experiment Details Ace View
Laboratory  CF
RNAi Reagent & Type  probe_1:SUPERLINK_RW5 (Unknown_reagent_type)
Reference  Yang L et al. (2005) Development "The roles of two C. elegans HOX co-factor orthologs in cell migration and vulva ...."
Delivery Method  Bacterial_feeding
Date  2004-10-26
Gene Plot of Y75B8A.2 Browse using GBrowse
Gene Graph
Gene Plot of T28F12.2 Browse using GBrowse
Gene Graph
Gene Plot of Y47D3A.5 Browse using GBrowse
Gene Graph