| Ace View of WBRNAi00059919 | ||||||
| Gene Inhibited | Y65B4A.8 | |||||
| Description of "Y65B4A.8" | Associated GO Term : nucleotidyltransferase activity | |||||
| KOG Annotation | Predicted nucleotidyltransferase Similar to bacterial dephospho-CoA kinase |
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| Evidence for Inhibition |
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| External "Y65B4A.8" Links |   |
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| Gene Inhibited | ZK256.1 (pmr-1) | |||||
| Description of "ZK256.1" | The pmr-1 gene encodes a Golgi P-type ATPase Ca^2+/Mn^2+-pump; mutations in its human ortholog, ATP2C1, cause Hailey-Hailey disease (OMIM:169600). | |||||
| KOG Annotation | Ca2+ transporting ATPase |
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| Evidence for Inhibition |
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| External "ZK256.1" Links | |
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| Gene Inhibited | F57G9.6 | |||||
| Evidence for Inhibition |
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| External "F57G9.6" Links | |
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| Gene Inhibited | F12A10.6 | |||||
| KOG Annotation | Serine/threonine kinase (haspin family) |
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| Evidence for Inhibition |
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| External "F12A10.6" Links | |
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| Phenotype | Stress Resistance
Simultaneous knock down of pmr-1 and smf-3 could effectively increase the survival rate of smf-3 RNAi worms to the level of wild type worms. |
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| Laboratory | KJ | |||||
| RNAi Reagent & Type | yk218a11 (cDNA_reagent) | |||||
| Strain | N2 | |||||
| Reference | Cho JH et al. (2005) FEBS Lett "Caenorhabditis elegans PMR1, a P-type calcium ATPase, is important for ...." | |||||
| Delivery Method | Injection | |||||
| Date | 2004-12-09 | |||||
| Gene Plot of ZK256.1 | ||||||
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| Gene Plot of Y65B4A.8 | ||||||
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| Gene Plot of F57G9.6 | ||||||
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| Gene Plot of F12A10.6 | ||||||
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