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RNAi Experiment: WBRNAi00059925 Ace View of WBRNAi00059925
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  DY3.2 (lmn-1)
Description of "DY3.2"  The lmn-1 gene encodes a nuclear lamin; LMN-1 protein is essential for the nuclear envelope localization of emerin (EMR-1) protein during during early development.
KOG Annotation  Nuclear envelope protein lamin, intermediate filament superfamily
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1575
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "DY3.2" Links  Wormbase NCBI
WBRNAi00059925 Phenotypes Help with Phenotypes
Phenotype  Unclassified lmn-1(RNAi) embryos exhibit defects in localization of nuclear membrane components. In the lmn-1(RNAi) mutant background, UNC-84 is not detectable at the nuclear envelope, nucleoporins are clustered to one side of the nucleus, and EMR-1 is displaced from the nuclear envelope, similar to UNC-84.
WBRNAi00059925 Experiment Details Ace View
Laboratory  YG
RNAi Reagent & Type  probe_1:DY3 (Unknown_reagent_type)
Reference  Lee KK et al. (2002) Molecular Biology of the Cell "Lamin-dependent localization of UNC-84, a protein required for nuclear ...."
Delivery Method  Injection
Date  2001-11-29
Gene Plot of DY3.2 Browse using GBrowse
Gene Graph