RNAi Experiment: WBRNAi00060160 |
Ace View of WBRNAi00060160
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Genes Inhibited |
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Gene Inhibited |
F43C1.2 (mpk-1) |
Description of "F43C1.2" |
mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro. |
KOG Annotation  |
Mitogen-activated protein kinase
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (III:4217371..4218826)
Transcript overlap: 815 nt |
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Sliding Window |
Raw score: 773
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F43C1.2" Links |
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WBRNAi00060160 Phenotypes |
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Phenotype |
WT
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WBRNAi00060160 Experiment Details |
Ace View |
Laboratory |
KP |
RNAi Reagent & Type |
sjj_F43C1.2 (PCR_reagent) |
Reference |
Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." |
Delivery Method |
Bacterial_feeding |
Date |
2005-5-09 |
Gene Plot of F43C1.2 |
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