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RNAi Experiment: WBRNAi00060162 Ace View of WBRNAi00060162
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F43C1.2 (mpk-1)
Description of "F43C1.2"  mpk-1 encodes a mitogen-activated protein (MAP) kinase that acts in the vulval precursor cells to affect LET-60(Ras)-mediated induction of vulval cell fates, and also affects larval viability, morphology of the male spicules, and acts in combination with mek-2 to permit germ cell exit from the pachytene stage of first meiotic prophase; both LIN-1 and LIN-31 act genetically downstream of mpk-1 with respect to vulval induction, and LIN-1 and LIN-31 are substrates for MPK-1 in vitro.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:4217371..4218826)
Transcript overlap: 815 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 773
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F43C1.2" Links  Wormbase NCBI
WBRNAi00060162 Phenotypes Help with Phenotypes
Larval  Let
WBRNAi00060162 Experiment Details Ace View
Laboratory  KP
RNAi Reagent & Type  sjj_F43C1.2 (PCR_reagent)
Reference  Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...."
Delivery Method  Bacterial_feeding
Date  2005-5-09
Gene Plot of F43C1.2 Browse using GBrowse
Gene Graph