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RNAi Experiment: WBRNAi00060288 Ace View of WBRNAi00060288
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  B0348.4 (egl-8)
Description of "B0348.4"  egl-8 encodes a phospholipase C beta homolog that affects pharyngeal pumping, defecation, and activity levels; it is genetically downstream of egl-30 with respect to aldicarb-induced paralysis, and is expressed in most or all neurons, with the strongest staining in the head and tail ganglia, and in the intestine.
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:24612..26121)
Transcript overlap: 737 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 632
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "B0348.4" Links  Wormbase NCBI
WBRNAi00060288 Phenotypes Help with Phenotypes
Phenotype  aldicarb_resistant Animals displayed resistance to paralysis on aldicarb in 4 out of 4 trials.
WBRNAi00060288 Experiment Details Ace View
Laboratory  KP
RNAi Reagent & Type  sjj_B0348.4 (PCR_reagent)
Reference  Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...."
Delivery Method  Bacterial_feeding
Date  2005-5-09
Gene Plot of B0348.4 Browse using GBrowse
Gene Graph