RNAi Experiment: WBRNAi00060288 |
Ace View of WBRNAi00060288
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Genes Inhibited |
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Gene Inhibited |
B0348.4 (egl-8) |
Description of "B0348.4" |
egl-8 encodes a phospholipase C beta homolog that affects pharyngeal pumping, defecation, and activity levels; it is genetically downstream of egl-30 with respect to aldicarb-induced paralysis, and is expressed in most or all neurons, with the strongest staining in the head and tail ganglia, and in the intestine. |
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (V:24612..26121)
Transcript overlap: 737 nt |
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Sliding Window |
Raw score: 632
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "B0348.4" Links |
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WBRNAi00060288 Phenotypes |
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Phenotype |
aldicarb_resistant
Animals displayed resistance to paralysis on aldicarb in 4 out of 4 trials.
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WBRNAi00060288 Experiment Details |
Ace View |
Laboratory |
KP |
RNAi Reagent & Type |
sjj_B0348.4 (PCR_reagent) |
Reference |
Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...." |
Delivery Method |
Bacterial_feeding |
Date |
2005-5-09 |
Gene Plot of B0348.4 |
Browse using GBrowse
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