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RNAi Experiment: WBRNAi00060776 Ace View of WBRNAi00060776
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F23F12.6 (rpt-3)
Description of "F23F12.6"  rpt-3 encodes a triple A ATPase subunit of the 26S proteasome's 19S regulatory particle (RP) base subcomplex; RPT-3 is required for embryonic, larval, and germline development and by homology, is predicted to function in unfolding protein substrates and translocating them into the core proteolytic particle (CP) of the proteasome.
KOG Annotation  26S proteasome regulatory complex, ATPase RPT3
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:6489749..6490751)
Transcript overlap: 868 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 805
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F23F12.6" Links  Wormbase NCBI
WBRNAi00060776 Phenotypes Help with Phenotypes
Phenotype  aldicarb_resistant Animals displayed resistance to paralysis on aldicarb in 7 out of 8 trials.
WBRNAi00060776 Experiment Details Ace View
Laboratory  KP
RNAi Reagent & Type  sjj_F23F12.6 (PCR_reagent)
Reference  Sieburth D et al. (2005) Nature "Systematic analysis of genes required for synapse structure and ...."
Delivery Method  Bacterial_feeding
Date  2005-5-09
Gene Plot of F23F12.6 Browse using GBrowse
Gene Graph