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RNAi Experiment: [cgc4120]:lag-3 Ace View of [cgc4120]:lag-3
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C32A3.1 (sel-8)
Description of "C32A3.1"  sel-8 encodes a nuclear protein required for LIN-12 and GLP-1 signalling; SEL-8 contains a novel motif shared with W09C5.1 and orthologs of W09C5.1 in S. cerevisiae (YER126c), Drosophila (DMIP259), and also has two prominent glutamine-rich domains.
Evidence for Inhibition 
Sliding Window Raw score: 1432
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C32A3.1" Links  Wormbase NCBI
[cgc4120]:lag-3 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance None reported
Adult  Pvl animals were soaked in dsRNA as L1, 36% of adults had a protruding vulva
Phenotype  Glp animals were soaked in dsRNA as L1, 91% of adults were sterile
Unclassified RNAi was performed in glp-1(oz112) background at 25 degrees C. 30% animals were Glp, 30% fertile, 28% tumorous, 11% exploaded through vulva
[cgc4120]:lag-3 Experiment Details Ace View
RNAi Reagent & Type  [cgc4120]:C32A3.1a (cDNA_reagent)
Reference  Petcherski AG et al. (2000) Nature "LAG-3 is a putative transcriptional activator in the C. elegans Notch ...."
Delivery Method  Soaking
Date  2000-3-03
Gene Plot of C32A3.1 Browse using GBrowse
Gene Graph