RNAi Experiment: [cgc4120]:lag-3 |
Ace View of [cgc4120]:lag-3
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Genes Inhibited |
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Gene Inhibited |
C32A3.1 (sel-8) |
Description of "C32A3.1" |
sel-8 encodes a nuclear protein required for LIN-12 and GLP-1 signalling; SEL-8 contains a novel motif shared with W09C5.1 and orthologs of W09C5.1 in S. cerevisiae (YER126c), Drosophila (DMIP259), and also has two prominent glutamine-rich domains. |
Evidence for Inhibition |
Sliding Window |
Raw score: 1432
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "C32A3.1" Links |
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[cgc4120]:lag-3 Phenotypes |
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Embryonic |
Emb Penetrance None reported |
Adult |
Pvl
animals were soaked in dsRNA as L1, 36% of adults had a protruding vulva
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Phenotype |
Glp
animals were soaked in dsRNA as L1, 91% of adults were sterile Unclassified
RNAi was performed in glp-1(oz112) background at 25 degrees C. 30% animals were Glp, 30% fertile, 28% tumorous, 11% exploaded through vulva
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[cgc4120]:lag-3 Experiment Details |
Ace View |
RNAi Reagent & Type |
[cgc4120]:C32A3.1a (cDNA_reagent) |
Reference |
Petcherski AG et al. (2000) Nature "LAG-3 is a putative transcriptional activator in the C. elegans Notch ...." |
Delivery Method |
Soaking |
Date |
2000-3-03 |
Gene Plot of C32A3.1 |
Browse using GBrowse
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