Link to C07F11.1RNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
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RNAi Experiment: [cgc4692]:tol-1 Ace View of [cgc4692]:tol-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C07F11.1 (tol-1)
Description of "C07F11.1"  The tol-1 gene encodes a predicted transmembrane protein that is the sole C. elegans Toll-like receptor (TLR); TOL-1 is required for proper embryonic development and for pathogen avoidance behavior, and is expressed primarily in the nervous system.
KOG Annotation  Toll/interleukin receptor and related proteins containing LRR and TIR repeats
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (I:457246..458564)
Transcript overlap: 1319 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 1298
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C07F11.1" Links  Wormbase NCBI
[cgc4692]:tol-1 Phenotypes Help with Phenotypes
Embryonic  Emb Penetrance 25 %
Adult  Bmd
[cgc4692]:tol-1 Experiment Details Ace View
Laboratory  IG
RNAi Reagent & Type  [cgc4692]:tol-1 (PCR_reagent)
Remark  Similar RNAi results when using cDNA yk412a2 as the template.
Reference  Pujol N et al. (2001) Current Biology "A reverse genetic analysis of components of the Toll signaling pathway in ...."
Delivery Method  Injection
Date  2001-6-05
Gene Plot of C07F11.1 Browse using GBrowse
Gene Graph