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RNAi Experiment: [cgc4697]:rab-8 Ace View of [cgc4697]:rab-8
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  D1037.4 (rab-8)
Description of "D1037.4"  rab-8 encodes a rab related protein of the Ras GTPase superfamily that affects ovarian morphology and function, thereby affecting fertility; acts downstream of let-60 with respect to vulval development based on genetic analysis.
KOG Annotation  GTP-binding protein SEC4, small G protein superfamily, and related Ras family GTP-binding proteins
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 852
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "D1037.4" Links  Wormbase NCBI
[cgc4697]:rab-8 Phenotypes Help with Phenotypes
Adult  Ste Severe deformation of the ovaries prevented any eggs from being produced.
[cgc4697]:rab-8 Experiment Details Ace View
Laboratory  WH
RNAi Reagent & Type  yk451h3 (cDNA_reagent)
Remark  template cDNA yk451h3, homologous to Rab8, see [cgc2918]
Reference  Skop AR et al. (2001) Current Biology "Completion of cytokinesis in C. elegans requires a brefeldin A-sensitive ...."
Delivery Method  Injection
Date  2001-5-15
Gene Plot of D1037.4 Browse using GBrowse
Gene Graph