| Ace View of [cgc4699]:zyg-1 | |||||||||
| Gene Inhibited | F59E12.2 (zyg-1) | ||||||||
| Description of "F59E12.2" | zyg-1 encodes a homolog of polo-like and calcium-dependent kinases that is required for daughter centriole formation; ZYG-1 localizes transiently to centrosomes and acts at least one cell cycle prior to each spindle assembly event; ZYG-1 activity is required for proper localization of the SAS-5 and SAS-6 coiled-coil proteins that are also required for centriole duplication. | ||||||||
| KOG Annotation | Ca2+/calmodulin-dependent protein kinase, EF-Hand protein superfamily |
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| Evidence for Inhibition |
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| External "F59E12.2" Links |   |
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| Embryonic | Emb Penetrance None reported | ||||||||
| Adult | Stp
resulted from partial RNAi effect Unc resulted from partial RNAi effect |
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| Laboratory | OC | ||||||||
| RNAi Reagent & Type | [cgc4699]:zyg-1 (PCR_reagent) | ||||||||
| Reference | O'Connell KF et al. (2001) Cell "The C. elegans zyg-1 gene encodes a regulator of centrosome duplication with ...." | ||||||||
| Delivery Method | Injection | ||||||||
| Date | 2001-5-18 | ||||||||
| Gene Plot of F59E12.2 | |||||||||
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