RNAi Experiment: [cgc5235]:itr-1.1 |
Ace View of [cgc5235]:itr-1.1
|
Genes Inhibited |
|
Gene Inhibited |
F33D4.2 (itr-1) |
Description of "F33D4.2" |
itr-1 encodes a putative inositol (1,4,5) trisphosphate receptor that affects the defecation cycle and pharyngeal pumping, and also affects ovulation in a pathway downstream of LET-23; interacts with UNC-54 in vivo, and is expressed in the adult intestine, pharynx, excretory cell, germ line, and spermatheca, with limited neuronal expression. |
KOG Annotation  |
Inositol 1,4,5-trisphosphate receptor
|
|
Evidence for Inhibition |
Sliding Window |
Raw score: 857
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
|
External "F33D4.2" Links |
|
[cgc5235]:itr-1.1 Phenotypes |
|
|
Phenotype |
Unclassified
itr-1 RNAi results in slower pharyngeal pumping in the presence of food; pumping rate is increased in response to serotonin, but is not fully restored to wild-type levels
|
[cgc5235]:itr-1.1 Experiment Details |
Ace View |
Laboratory |
HB |
RNAi Reagent & Type |
[cgc5235]:itr-1.1 (cDNA_reagent) |
Strain |
N2 |
Reference |
Walker DS et al. (2002) Molecular Biology of the Cell "Regulated disruption of inositol 1,4,5-trisphosphate signaling in ...." |
Delivery Method |
Bacterial_feeding |
Date |
2002-1-18 |
Gene Plot of F33D4.2 |
Browse using GBrowse
|
|