Ace View of [cgc5346]:csb-1 | ||||||
Gene Inhibited | F53H4.1 (csb-1) | |||||
Description of "F53H4.1" | csb-1 is orthologous to human gene ERCC6 (OMIM:133530, mutated in Cockayne syndrome); CSB-1 is required for embryonic viability, and represses UV-induced apoptosis in germ cells. | |||||
KOG Annotation  | Transcription-coupled repair protein CSB/RAD26 (contains SNF2 family DNA-dependent ATPase domain) |
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Evidence for Inhibition |
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External "F53H4.1" Links | ||||||
Embryonic | Emb Penetrance None reported | |||||
Phenotype | Unclassified
csb-1 RNAi results in an increased UV-induced apoptosis in the germ cells |
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RNAi Reagent & Type | yk646a6 (cDNA_reagent) | |||||
Strain | WT | |||||
Reference | Lee MH et al. (2002) FEBS Letters "The gene expression and deficiency phenotypes of Cockayne syndrome B protein in ...." | |||||
Delivery Method | Injection | |||||
Date | 2002-5-07 | |||||
Gene Plot of F53H4.1 | ||||||