RNAi Experiment: [cgc5655]:C47D12.7 |
Ace View of [cgc5655]:C47D12.7
|
Genes Inhibited |
|
Gene Inhibited |
C47D12.7 (kel-1) |
Description of "C47D12.7" |
kel-1 encodes a BTB/POZ- and Kelch motif-containing protein orthologous to Drosophila Kelch, which is essential for actin organization in ovarian ring canals; in C. elegans, kel-1 is required for regulating feeding during larval development and more specifically, for pharyngeal isthmus peristalsis and efficient trapping of food in the pharynx; KEL-1 is first expressed at the 1.5-fold stage of embryogenesis in the pharyngeal lumen and the nerve ring; later adult and larval expression is confined to the pharyngeal gland cells in which KEL-1 may be required for maintenance of gland cell-specific structures. |
KOG Annotation  |
Proteins containing BTB/POZ and Kelch domains, involved in regulatory/signal transduction processes
|
|
Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:11690251..11691273)
Transcript overlap: 764 nt |
|
Sliding Window |
Raw score: 619
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
|
External "C47D12.7" Links |
|
Gene Inhibited |
C47D12.6 (trs-1) |
Description of "C47D12.6" |
This gene encodes a protein predicted by Eisenberg and coworkers, with 52% accuracy, to be mitochondrial. |
Evidence for Inhibition |
ePCR |
Transcript overlap: 40 nt |
|
|
External "C47D12.6" Links |
|
[cgc5655]:C47D12.7 Phenotypes |
|
|
Phenotype |
Unclassified
lipid metabolism abnormal
|
[cgc5655]:C47D12.7 Experiment Details |
Ace View |
Laboratory |
GR |
RNAi Reagent & Type |
sjj_C47D12.7 (PCR_reagent) |
Reference |
Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." |
Delivery Method |
Bacterial_feeding |
Date |
2003-1-10 |
Gene Plot of C47D12.7 |
Browse using GBrowse
|
|
Gene Plot of C47D12.6 |
Browse using GBrowse
|
|