RNAi Experiment: [cgc5655]:E04F6.3 |
Ace View of [cgc5655]:E04F6.3
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Genes Inhibited |
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Gene Inhibited |
E04F6.3 (maoc-1) |
Description of "E04F6.3" |
E04F6.3 encodes a protein that is orthologous (with 52% identity over 93% of its length) to residues 334-609 of human 17-BETA-HYDROXYSTEROID DEHYDROGENASE IV (HSD17B4; OMIM:601860, mutated in D-bifunctional protein deficiency), a protein of 736 residues whose N- and C-terminal domains are orthologous to DHS-28; E04F6.3 contains a MaoC-like domain, found in diverse enzymes (HSD17B4, peroxisomal hydratase-dehydrogenase-epimerase, and the fatty acid synthase beta subunit); E04F6.3 has no obvious function in mass RNAi assays. |
KOG Annotation  |
Peroxisomal multifunctional beta-oxidation protein and related enzymes
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (II:7196410..7197299)
Transcript overlap: 781 nt |
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Sliding Window |
Raw score: 718
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "E04F6.3" Links |
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[cgc5655]:E04F6.3 Phenotypes |
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Phenotype |
Unclassified
lipid metabolism abnormal
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[cgc5655]:E04F6.3 Experiment Details |
Ace View |
Laboratory |
GR |
RNAi Reagent & Type |
sjj_E04F6.3 (PCR_reagent) |
Reference |
Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." |
Delivery Method |
Bacterial_feeding |
Date |
2003-1-10 |
Gene Plot of E04F6.3 |
Browse using GBrowse
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