RNAi Experiment: [cgc5655]:F14D12.2 |
Ace View of [cgc5655]:F14D12.2
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Genes Inhibited |
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Gene Inhibited |
F14D12.2 (unc-97) |
Description of "F14D12.2" |
The unc-97 gene encodes a LIM domain-containing protein of the PINCH family that is highly similar to human LIMS1 (OMIM:602567) and LIMS2; UNC-97 functions as an adaptor protein important for assembly of muscle adherens junctions and the mechanosensory functions of the touch neurons; UNC-97 interacts with PAT-4/integrin-linked kinase and with UNC-98; UNC-97 colocalizes with PAT-3/beta integrin at dense bodies, focal adhesion-like muscle attachment structures. |
KOG Annotation  |
Focal adhesion protein PINCH-1, contains LIM domains
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Evidence for Inhibition |
ePCR |
Status: Unique_ePCR (X:5593237..5594405)
Transcript overlap: 863 nt |
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Sliding Window |
Raw score: 716
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F14D12.2" Links |
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[cgc5655]:F14D12.2 Phenotypes |
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Phenotype |
Unclassified
lipid metabolism abnormal
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[cgc5655]:F14D12.2 Experiment Details |
Ace View |
Laboratory |
GR |
RNAi Reagent & Type |
sjj_F14D12.2 (PCR_reagent) |
Reference |
Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...." |
Delivery Method |
Bacterial_feeding |
Date |
2003-1-10 |
Gene Plot of F14D12.2 |
Browse using GBrowse
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