Link to F14D12.2RNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAiRNAi ReagentRNAi ReagentRNAi ReagentgeneMap
Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 
RNAi Experiment: [cgc5655]:daf-2:F14D12.2 Ace View of [cgc5655]:daf-2:F14D12.2
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  F14D12.2 (unc-97)
Description of "F14D12.2"  The unc-97 gene encodes a LIM domain-containing protein of the PINCH family that is highly similar to human LIMS1 (OMIM:602567) and LIMS2; UNC-97 functions as an adaptor protein important for assembly of muscle adherens junctions and the mechanosensory functions of the touch neurons; UNC-97 interacts with PAT-4/integrin-linked kinase and with UNC-98; UNC-97 colocalizes with PAT-3/beta integrin at dense bodies, focal adhesion-like muscle attachment structures.
KOG Annotation  Focal adhesion protein PINCH-1, contains LIM domains
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:5593237..5594405)
Transcript overlap: 863 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 716
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F14D12.2" Links  Wormbase NCBI
[cgc5655]:daf-2:F14D12.2 Phenotypes Help with Phenotypes
Phenotype  Unclassified lipid metabolism abnormal
[cgc5655]:daf-2:F14D12.2 Experiment Details Ace View
Laboratory  GR
RNAi Reagent & Type  sjj_F14D12.2 (PCR_reagent)
Strain  daf-2(e1370)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Delivery Method  Bacterial_feeding
Date  2003-1-10
Gene Plot of F14D12.2 Browse using GBrowse
Gene Graph