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RNAi Experiment: [cgc5655]:daf-2:K10B3.7 Ace View of [cgc5655]:daf-2:K10B3.7
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K10B3.7 (gpd-3)
Description of "K10B3.7"  gpd-3 encodes a predicted glyceraldehyde 3-phosphate dehydrogenase that affects embryonic viability; GPD-3 interacts with LIN-2 in two-hybrid assays.
KOG Annotation  Glyceraldehyde 3-phosphate dehydrogenase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (X:3112282..3113406)
Transcript overlap: 996 nt
Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 893
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.464
Wormbase (BLAST) RNAi primary
External "K10B3.7" Links  Wormbase NCBI
Gene Inhibited  K10B3.9 (mai-1)
Description of "K10B3.9"  mai-1 encodes a protein with similarity to human mitochondrial ATPase inhibitor; exists as the upstream gene in an operon with gpd-2 and gpd-3.
Evidence for Inhibition 
Sliding Window Raw score: 527
Relative score: 0.59 (Best raw score= for Gene )
Specificity index: 0.274
External "K10B3.9" Links  Wormbase NCBI
Gene Inhibited  K10B3.8 (gpd-2)
Description of "K10B3.8"  gpd-2 encodes one of four C. elegans glyceraldehyde-3-phosphate dehydrogenases (GAPDHs); by homology, GPD-2 is predicted to reversibly catalyze the oxidation and phosphorylation of glyceraldehyde-3-phosphate to 1,3-diphosphoglycerate during glycolysis; in C. elegans, GPD-2 and GPD-3 constitute the major GAPDH isoenzymes and are expressed at highest levels during postembryonic development, primarily in the actin-containing A and I zones of body-wall muscle; loss of gpd-2 function via RNA-mediated interference (RNAi) does not result in any abnormalities.
KOG Annotation  Glyceraldehyde 3-phosphate dehydrogenase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 506
Relative score: 0.567 (Best raw score= for Gene )
Specificity index: 0.263
Wormbase (BLAST) RNAi primary
External "K10B3.8" Links  Wormbase NCBI
[cgc5655]:daf-2:K10B3.7 Phenotypes Help with Phenotypes
Phenotype  Unclassified lipid metabolism abnormal
[cgc5655]:daf-2:K10B3.7 Experiment Details Ace View
Laboratory  GR
RNAi Reagent & Type  sjj_K10B3.7 (PCR_reagent)
Strain  daf-2(e1370)
Reference  Ashrafi K et al. (2003) Nature "Genome-wide RNAi analysis of Caenorhabditis elegans fat regulatory ...."
Delivery Method  Bacterial_feeding
Date  2003-1-10
Gene Plot of K10B3.9 Browse using GBrowse
Gene Graph
Gene Plot of K10B3.7 Browse using GBrowse
Gene Graph
Gene Plot of K10B3.8 Browse using GBrowse
Gene Graph