Ace View of [cgc5674]:C03G5.1.1 | ||||||
Gene Inhibited | C03G5.1 | |||||
Description of "C03G5.1" | C03G5.1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA; OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome. | |||||
KOG Annotation  | Succinate dehydrogenase, flavoprotein subunit |
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Evidence for Inhibition |
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External "C03G5.1" Links | ||||||
Phenotype | Unclassified
25% of mev-1(kn1) animals survive RNAi treatment at 5% oxygen. 0% of mev-1(kn1) animals survive RNAi treatment at 30% oxygen. |
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RNAi Reagent & Type | [cgc5674]:C03G5.1.1 (PCR_reagent) | |||||
Reference | Ichimiya H et al. (2002) Mitochondrion "Complex II inactivation is let al. in the nematode" | |||||
Delivery Method | Bacterial_feeding | |||||
Gene Plot of C03G5.1 | ||||||