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RNAi Experiment: [cgc5674]:C03G5.1.1 Ace View of [cgc5674]:C03G5.1.1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  C03G5.1
Description of "C03G5.1"  C03G5.1 is orthologous to the human gene SUCCINATE DEHYDROGENASE COMPLEX, SUBUNIT A, FLAVOPROTEIN (SDHA; OMIM:600857), which when mutated leads to complex II mitochondrial respiratory chain deficiency presenting as Leigh syndrome.
KOG Annotation  Succinate dehydrogenase, flavoprotein subunit
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1511
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "C03G5.1" Links  Wormbase NCBI
[cgc5674]:C03G5.1.1 Phenotypes Help with Phenotypes
Phenotype  Unclassified 25% of mev-1(kn1) animals survive RNAi treatment at 5% oxygen. 0% of mev-1(kn1) animals survive RNAi treatment at 30% oxygen.
[cgc5674]:C03G5.1.1 Experiment Details Ace View
RNAi Reagent & Type  [cgc5674]:C03G5.1.1 (PCR_reagent)
Reference  Ichimiya H et al. (2002) Mitochondrion "Complex II inactivation is let al. in the nematode"
Delivery Method  Bacterial_feeding
Gene Plot of C03G5.1 Browse using GBrowse
Gene Graph