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RNAi Experiment: [cgc5709]:pmk-1 Ace View of [cgc5709]:pmk-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  B0218.3 (pmk-1)
Description of "B0218.3"  pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway.
KOG Annotation  Mitogen-activated protein kinase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 1050
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "B0218.3" Links  Wormbase NCBI
[cgc5709]:pmk-1 Phenotypes Help with Phenotypes
Phenotype  Unclassified suppresses Salmonella enterica induced cell death
[cgc5709]:pmk-1 Experiment Details Ace View
RNAi Reagent & Type  [cgc5709]:B0218.3 (cDNA_reagent)
Reference  Aballay A et al. (2003) Current Biology "Caenorhabditis elegans innate immune response triggered by Salmonella ...."
Delivery Method  Soaking
Date  2002-10-11
Gene Plot of B0218.3 Browse using GBrowse
Gene Graph