Ace View of [cgc5709]:pmk-1 | ||||||
Gene Inhibited | B0218.3 (pmk-1) | |||||
Description of "B0218.3" | pmk-1 encodes a mitogen-activated protein kinase (MAPK), orthologous to human p38 MAPK (OMIM:600289), that is required for eliciting gonadal programmed cell death in response to Salmonella enterica infection; PMK-1 lies upstream of CED-9, a negative regulator of apoptosis, in the programmed cell death pathway. | |||||
KOG Annotation  | Mitogen-activated protein kinase |
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Evidence for Inhibition |
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External "B0218.3" Links | ||||||
Phenotype | Unclassified
suppresses Salmonella enterica induced cell death |
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RNAi Reagent & Type | [cgc5709]:B0218.3 (cDNA_reagent) | |||||
Reference | Aballay A et al. (2003) Current Biology "Caenorhabditis elegans innate immune response triggered by Salmonella ...." | |||||
Delivery Method | Soaking | |||||
Date | 2002-10-11 | |||||
Gene Plot of B0218.3 | ||||||