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RNAi Experiment: [cgc5728]:elo-1 Ace View of [cgc5728]:elo-1
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  Y50D7A.7 (ads-1)
Description of "Y50D7A.7"  ads-1 encodes an ortholog of human ALKYL-DIHYDROXYACETONEPHOSPHATE SYNTHASE PRECURSOR (AGPS; OMIM:603051) that is required for normal larval development; mutation of human AGPS leads to type 3 rhizomelic chondrodysplasia punctata (OMIM:600121).
KOG Annotation  Alkyl-dihydroxyacetonephosphate synthase
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (III:295712..298530)
Transcript overlap: 1794 nt		 Explain types of evidence for RNAi inhibition
External "Y50D7A.7" Links  Wormbase NCBI
Gene Inhibited  F56H11.4 (elo-1)
Description of "F56H11.4"  elo-1 encodes a component of C-18 polyunsaturated fatty acid (PUFA) elongase that is required for normal elongation of n-6 and n-3 20-carbon PUFA in vivo; ELO-1 is a condensing enzyme that elongates n-6 and n-7 (and, with less efficiency, n-3) series C18 PUFAs.
KOG Annotation  Long chain fatty acid elongase
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 286
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "F56H11.4" Links  Wormbase NCBI
[cgc5728]:elo-1 Phenotypes Help with Phenotypes
Phenotype  Unclassified Abnormal fatty acid composition
[cgc5728]:elo-1 Experiment Details Ace View
RNAi Reagent & Type  [cgc5728]:elo-1 (PCR_reagent)
Reference  Kniazeva M et al. (2003) Genetics "Suppression of the ELO-2 FA elongation activity results in alterations of the ...."
Delivery Method  Bacterial_feeding
Date  2002-10-23
Gene Plot of F56H11.4 Browse using GBrowse
Gene Graph
Gene Plot of Y50D7A.7 Browse using GBrowse
Gene Graph