RNAi Experiment: [cgc5728]:elo-2b |
Ace View of [cgc5728]:elo-2b
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Genes Inhibited |
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Gene Inhibited |
F11E6.5 (elo-2) |
Description of "F11E6.5" |
The elo-2 gene encodes a palmitic acid elongase, homologous to polyunsaturated fatty acid (PUFA) elongases such as ELO-1, that is required for normally rapid growth, normally large body size, fertility, and for the quantitative regulation of the ultradian defecation rhythm; the joint action of ELO-2 with ELO-1 is strongly required for 20-carbon PUFA production and for general viability; elo-2 is most strongly expressed in intestinal cells, as well as other tissues such as the ventral nerve cord, pharyngeal muscles, uterus, and tail. |
KOG Annotation  |
Long chain fatty acid elongase
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Evidence for Inhibition |
Sliding Window |
Raw score: 641
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene) |
Wormbase (BLAST) |
RNAi primary |
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External "F11E6.5" Links |
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[cgc5728]:elo-2b Phenotypes |
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Phenotype |
Unclassified
in fat-2(wa17) background the frequency of posterior body wall muscle contractions is lowered
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[cgc5728]:elo-2b Experiment Details |
Ace View |
RNAi Reagent & Type |
[cgc5728]:elo-2b (PCR_reagent) |
Reference |
Kniazeva M et al. (2003) Genetics "Suppression of the ELO-2 FA elongation activity results in alterations of the ...." |
Delivery Method |
Bacterial_feeding |
Date |
2002-10-23 |
Gene Plot of F11E6.5 |
Browse using GBrowse
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