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RNAi Experiment: [pmid12709403]:coq-5 Ace View of [pmid12709403]:coq-5
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  ZK652.10 (tag-307)
KOG Annotation  Putative Mg2+ and Co2+ transporter CorD
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 503
Relative score: 0.867 (Best raw score= for Gene )
Specificity index: 0.464
Wormbase (BLAST) RNAi primary
External "ZK652.10" Links  Wormbase NCBI
Gene Inhibited  ZK652.9 (coq-5)
Description of "ZK652.9"  coq-5 encodes a putative ubiquinone biosynthesis methyltransferase, homologous to COQ5 in S. cerevisiae and a family of methyltransferases involved in ubiquinone, menaquinone, biotin and sterol biosynthesis and in phosphatidylethanolamine methylation; COQ-5 is required for ubiquinone biosynthesis and for normally short lifespan; coq-5(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans.
KOG Annotation  Ubiquinone biosynthesis methyltransferase COQ5
What's a KOG?
Evidence for Inhibition 
Sliding Window Raw score: 580
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 0.536
Wormbase (BLAST) RNAi primary
External "ZK652.9" Links  Wormbase NCBI
[pmid12709403]:coq-5 Phenotypes Help with Phenotypes
Phenotype  Age
Unclassified decrease in superoxide production
[pmid12709403]:coq-5 Experiment Details Ace View
RNAi Reagent & Type  [pmid12709403]:coq-5 (PCR_reagent)
Reference  Asencio C et al. (2003) FASEB J "Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis ...."
Delivery Method  Bacterial_feeding
Date  2003-4-22
Gene Plot of ZK652.10 Browse using GBrowse
Gene Graph
Gene Plot of ZK652.9 Browse using GBrowse
Gene Graph