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RNAi Experiment: [pmid12709403]:coq-6 Ace View of [pmid12709403]:coq-6
Genes Inhibited How is RNAi inhibition determined?
Gene Inhibited  K07B1.2 (coq-6)
Description of "K07B1.2"  coq-6 encodes a putative aromatic-ring monooxygenase, homologous to yeast COQ6; COQ-6 is required for ubiquinone biosynthesis and for normally short lifespan; coq-6(RNAi) animals have reduced levels of coenzyme Q8, coenzyme Q9, and superoxide, and have abnormally long lifespans.
KOG Annotation  Monooxygenase involved in coenzyme Q (ubiquinone) biosynthesis
What's a KOG?
Evidence for Inhibition 
ePCR Status: Unique_ePCR (V:9339403..9341206)
Transcript overlap: 1078 nt		 Explain types of evidence for RNAi inhibition
Sliding Window Raw score: 910
Relative score: 1 (This gene has the best score for this RNAi reagent)
Specificity index: 1 (RNAi reagent is specific for this gene)
Wormbase (BLAST) RNAi primary
External "K07B1.2" Links  Wormbase NCBI
[pmid12709403]:coq-6 Phenotypes Help with Phenotypes
Phenotype  Age
Unclassified decrease in superoxide production
[pmid12709403]:coq-6 Experiment Details Ace View
RNAi Reagent & Type  [pmid12709403]:coq-6 (PCR_reagent)
Reference  Asencio C et al. (2003) FASEB J "Silencing of ubiquinone biosynthesis genes extends life span in Caenorhabditis ...."
Delivery Method  Bacterial_feeding
Date  2003-4-22
Gene Plot of K07B1.2 Browse using GBrowse
Gene Graph