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Gene: C04G2.4   

C04G2.4SMapS_parentSequenceC04G2
ChromosomeIV
Identity (5)
Gene_info Gene_classmsp
Phenotype[C.elegansII] NMK. Encodes MSP (16kD); msp-77 cluster. [Ward et al. (1988); BA]
GO_termGO:0005198 IEA Inferred_automatically
Structured_description Provisional_descriptionmsp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes. Paper_evidence WBPaper00001023
WBPaper00002143
WBPaper00004591
WBPaper00005670
Curator_confirmedWBPerson324
Date_last_updated22 Mar 2005 00:00:00
Concise_descriptionmsp-36 encodes a protein that belongs to a family of proteins called the Major Sperm Proteins (MSPs) that is conserved in nematodes; this family comprises of closely related, small, basic proteins that make up 15% of sperm protein; this multigene family consists of over fifty genes, including many pseudogenes; MSP is involved in both extracellular signaling and cytoskeletal functions during reproduction-MSP antagonizes Eph/ephrin signaling, in part, by binding VAB-1 Eph receptor tyrosine kinase on oocytes and sheath cells to promote oocyte maturation and MAPK activation; MSP assembles into fibrous networks that drives movement of the C. elegans sperm; msp genes are expressed only in late primary spermatocytes.
Molecular_info Corresponding_CDSC04G2.4
Corresponding_proteinWP:CE03853
Corresponding_PCR_product (44)
Corresponding_RNAi_reagent Cenix:242-d2
sjj_C04G2.4
mv_ZK354.4
sjj_ZK354.11
Cenix:14-e7
Cenix:238-b12
sjj_C34F11.4
sjj_F32B6.6
sjj_R13H9.2
sjj_ZK354.1
mv_ZK1251.6
yk381d1
mv_C34F11.4
sjj_K08F4.8
sjj_F36H12.7
sjj_F58A6.8
Cenix:16-c9
Cenix:241-h1
mv_F36H12.7
sjj_K07F5.3
sjj_F26G1.7
Cenix:246-b8
Cenix:242-c6
sjj_Y59E9_120.c
Cenix:242-h7
Cenix:242-h2
sjj_K07F5.1
mv_C09B9.6
mv_F26G1.7
sjj_R05F9.13
sjj_T13F2.11
Cenix:205-e12
Cenix:14-g4
Cenix:245-g4
sjj_Y4C6A.c
sjj_T13F2.10
Cenix:13-f11
sjj_K07F5.2
Cenix:13-d7
yk384g8
sjj_R13H9.4
sjj_ZK1251.6
mv_Y59H11AM.d
sjj_C09B9.6
yk386a12
yk387c2
yk370d1
sjj_ZK354.5
mv_F32B6.6
Cenix:242-g2
Cenix:242-g7
sjj_ZK354.4
Experimental_info RNAi_result Cenix:242-d2
JA:C04G2.4
[cgc5655]:C04G2.4
WB_RNAi_result (75)
Expr_patternExpr3417
Reference WBPaper00001023
WBPaper00024312
MethodGene