Go to RNAiDB Home Adult Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie Wild-type C. elegans Movie
 

Gene: C43E11.7   

C43E11.7SMapS_parentSequenceC43E11
ChromosomeI
Identity (5)
Gene_info Gene_classndx
Allele (2)
Contained_in_operonCEOP1160
Structured_description Provisional_description (5)
Concise_descriptionndx-7 encodes a NUDIX hydrolase; by sequence comparison, NDX-7 is predicted to function as a pyrophosphatase, and is most closely related to the mouse RP2 protein that has unknown substrate specificity but is regulated transcriptionally by the presence of androgens; in C. elegans, loss of ndx-7 activity via RNA-mediated interference (RNAi) does not result in any obvious abnormalities, consistent with the proposed nonessential roles for Nudix proteins in eliminating potentially toxic nucleotide metabolites from cells and modulating levels of metabolic intermediates by shuttling them into alternative biochemical pathways.
Molecular_info (5)
Experimental_info RNAi_result Cenix:159-e1
JA:C43E11.7
WB_RNAi_result JA:C43E11.7
MV_SV:mv_C43E11.7
Cenix:159-e1
ReferenceWBPaper00005401
MethodGene