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Gene: F11C1.6   

F11C1.6Evidence Paper_evidence WBPaper00003416
WBPaper00004124
WBPaper00004329
SMapS_parentSequenceF11C1
ChromosomeX
Identity (5)
Gene_info Gene_classnhr
Allele jm2389 Inferred_automaticallyFrom strain object: HL2000
ok645 Inferred_automaticallyFrom strain object: VC469
ku217 Paper_evidenceWBPaper00024419
Phenotype[M Asahina] jm2389 is mutagenized using TMP/UV and detected a deletion by PCR. This removes the coding region from Gly40 in the P-box of the first zinc finger motif to Ser377 in the middle of the conserved region II within the LBD (ref. Asahina M et al. 2000 The conserved nuclear receptor Ftz-F1 is required for embryogenesis, moulting and reproduction in Caenorhabditis elegans. Genes to Cells 5: 711). Phenotype is homozygous embryonic lethal at 1.5-fold to 2-fold stage. Balanced with +/szT1[lon-2(e678)] I; nDf19/szT1 X (strain MT1401)
Strain HL2000
VC469
GO_term (6)
Structured_description Provisional_descriptionnhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods. Paper_evidence WBPaper00004329
WBPaper00006295
WBPaper00013324
Person_evidenceWBPerson567
Curator_confirmedWBPerson567
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionnhr-25 encodes a nuclear hormone receptor orthologous to Drosophila Ftz-F1; NHR-25 is required for embryogenesis, molting, vulval and gonadal development, and hypodermal expression of acn-1; nhr-25 is expressed in gonads and loaded into embryos as a maternal transcript; nhr-25 is zygotically expressed in progeny of the E cell, and then in hypodermis and gut; the role of NHR-25 in molting may be evolutionarily conserved between nematodes and arthopods.
Molecular_info (5)
Experimental_info RNAi_result (7)
WB_RNAi_result (14)
Expr_pattern Expr969
Expr970
Expr1132
Expr1133
Expr2871
Expr3035
Expr3137
Reference (27)
RemarkMap position created from combination of previous interpolated map position (based on known location of sequence) and allele information. Therefore this is not a genetic map position based on recombination frequencies or genetic experiments. This was done on advice of the CGC.CGC_data_submission
MethodGene