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Gene: F11C3.2   

F11C3.2EvidenceCGC_data_submission
SMapS_parentSequenceF11C3
ChromosomeI
Identity (5)
Gene_info Gene_classunc
Allele e2520 Inferred_automaticallyFrom strain object: CB4870
n2916 Paper_evidenceWBPaper00006427
Inferred_automaticallyFrom strain object: CB51
ox79 Paper_evidenceWBPaper00006427
Phenotype[C.elegansII] e2520 : medium coiler at all stages. Moves forward well when stimulated, tends to coil up when moving backwards or at rest. Coiling usually ventral, occasionally dorsal. ES2 ME1/ME2. NA1. [CB]
Strain CB51
CB4870
GO_term GO:0006817 IEA Inferred_automatically
GO:0005737 IEA Inferred_automatically
Structured_description Provisional_descriptionunc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known. Paper_evidence WBPaper00002665
WBPaper00012807
WBPaper00015718
WBPaper00017559
Person_evidenceWBPerson1843
Curator_confirmedWBPerson1843
Date_last_updated17 Jun 2004 00:00:00
Concise_descriptionunc-122 encodes a predicted type II transmembrane protein with extracellular collagen-like domains and a highly conserved olfactomedin (OLF) domain that is found in a family of secreted proteins involved in formation and function of nervous systems; UNC-122 is required for proper locomotion and for normal morphology of the DVB motorneuron, and may regulate neuromuscular function by acting in an aminergic/peptidergic pathway parallel to cholinergic neurotransmission; although mosaic analysis indicates that UNC-122 activity is required in muscle cells, the precise expression and localization patterns of UNC-122 are not yet known.
Molecular_info (6)
Experimental_info RNAi_resultCenix:147-a1
WB_RNAi_result MV_SV:mv_F11C3.2
Cenix:147-a1
Expr_pattern Expr2859
Expr2860
Expr5327
Interaction WBInteraction0002346
WBInteraction0002347
WBInteraction0002348
Reference (6)
Remark [Hodgkin JA] extracted from complex strain CB3337, isolated by Hedgecock EM
Sequence connection from [Loria P, Hobert O]
MethodGene